T: 6.875”
MEDICATION GUIDE FOR AMPYRA® (am-PEER-ah)
(dalfampridine) Extended Release Tablets
Read this Medication Guide before you start taking AMPYRA and each time you get a
refill. There may be new information. This information does not take the place of talking
with your doctor about your medical condition or your treatment.
What is the most important information I should know about AMPYRA?
AMPYRA can cause seizures.
• You could have a seizure even if you never had a seizure before.
• Your chance of having a seizure is higher if you take too much AMPYRA or if your
kidneys have a mild decrease of function, which is common after age 50.
• Your doctor may do a blood test to check how well your kidneys are working, if that
is not known before you start taking AMPYRA.
• Do not take AMPYRA if you have ever had a seizure.
• Before taking AMPYRA tell your doctor if you have kidney problems.
• Take AMPYRA exactly as prescribed by your doctor.
See “How do I take AMPYRA?”
Stop taking AMPYRA and call your doctor right away
if you have a seizure while taking AMPYRA.
What is AMPYRA?
AMPYRA is a prescription medicine used to help improve walking in people with
multiple sclerosis (MS). This was shown by an increase in walking speed.
It is not known if AMPYRA is safe or effective in children less than 18 years of age.
Who should not take AMPYRA?
Do not take AMPYRA if you:
• have ever had a seizure
• have certain types of kidney problems
What should I tell my doctor before taking AMPYRA?
Before you take AMPYRA, tell your doctor if you:
• have any other medical conditions
• are taking compounded 4-aminopyridine (fampridine, 4-AP)
• are pregnant or plan to become pregnant. It is not known if AMPYRA will harm your
unborn baby. You and your doctor will decide if you should take AMPYRA while you
are pregnant.
• are breast-feeding or plan to breast-feed. It is not known if AMPYRA passes into
your breast milk. You and your doctor should decide if you will take AMPYRA or
breast-feed. You should not do both.
Tell your doctor about all the medicines you take, including prescription and
non-prescription medicines, vitamins and herbal supplements.
Know the medicines you take. Keep a list of them and show it to your doctor and
pharmacist when you get a new medicine.
How should I take AMPYRA?
• Take AMPYRA exactly as your doctor tells you to take it. Do not change your dose of
AMPYRA.
• Take one tablet of AMPYRA 2 times each day about 12 hours apart. Do not take more
than 2 tablets of AMPYRA in a 24-hour period.
• Take AMPYRA tablets whole. Do not break, crush, chew or dissolve AMPYRA tablets
before swallowing. If you cannot swallow AMPYRA tablets whole, tell your doctor.
• AMPYRA is released slowly over time. If the tablet is broken, the medicine may be
released too fast. This can raise your chance of having a seizure.
• AMPYRA can be taken with or without food.
• If you miss a dose of AMPYRA, do not make up the missed dose. Do not take 2 doses
at the same time. Take your next dose at your regular scheduled time.
• If you take too much AMPYRA, call your doctor or go to the nearest hospital
emergency room right away.
• Do not take AMPYRA together with other aminopyridine medications, including
compounded 4-AP (sometimes called 4-aminopyridine, fampridine).
T: 9. 5”
