Brief Summary of Medication Guide
Injection for intramuscular use
Read this Medication Guide before you start using
AVONEX, and each time you get a refill. There may be new
information. This information does not take the place of
talking with your healthcare provider about your medical
condition or your treatment.
What is the most important information I should know
AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms
listed below while taking AVONEX.
1. Behavioral health problems including depression,
suicidal thoughts or hallucinations. Some people taking AVONEX may develop mood or behavior problems
2. Liver problems, or worsening of liver problems including liver failure and death. Symptoms may include:
and pale stools
During your treatment with AVONEX you will need to see
your healthcare provider regularly and have regular blood
tests to check for side effects.
3. Serious allergic reactions and skin reactions. Symptoms may include:
blisters and peels
What is AVONEX?
AVONEX is a form of a protein called beta interferon that
occurs naturally in the body. AVONEX is a prescription
medicine used to treat adults with relapsing forms of
had their first symptoms of multiple sclerosis and have an
MRI consistent with multiple sclerosis.
AVONEX will not cure your MS but may decrease the
number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common
in people with MS. MS is a life-long disease that affects
your nervous system by destroying the protective covering
The way AVONEX works in MS is not known.
It is not known if AVONEX is safe and effective in children.
Who should not use AVONEX?
Do not take AVONEX if you:
any of the ingredients in AVONEX. See the end of this
Medication Guide for a complete list of ingredients
What should I tell my healthcare provider before using
Before taking AVONEX, tell your healthcare provider if
the past for any mental illness, including depression and
the white part of your eye
•;Infections. Some people who take AVONEX may get an
infection. Symptoms of an infection may include:
° pain or burning with urination
° urinating often
° bloody diarrhea
° coughing up mucus
•;Thyroid problems. Some people taking AVONEX develop
changes in their thyroid function. Symptoms of thyroid
° problems concentrating
° feeling cold or hot all the time
° skin changes
Tell your healthcare provider right away if you have any of
the symptoms listed above.
The most common side effects of AVONEX include:
flu-like symptoms early during the course of therapy.
Usually, these symptoms last for a day after the injection.
You may be able to manage these flu-like symptoms by
many people, these symptoms lessen or go away over
time. Symptoms may include:
° muscle aches
How should I store AVONEX?
•;Do not;freeze;AVONEX.;Do not use AVONEX that has
•;Do not;store;AVONEX;above;77°F;( 25°C).
prefilled syringes, you can store your AVONEX PEN and
Keep AVONEX vials, prefilled syringes, pens and all other
medicines out of the reach of children.
General advice about the safe and effective use of
Medicines are sometimes prescribed for purposes other
than those listed in a Medication Guide. Do not use
AVONEX for a condition for which it was not prescribed.
Do not give AVONEX to other people, even if they have the
same symptoms that you have, it may harm them.
This;Medication;Guide;summarizes;the;most;important;in-formation about AVONEX. If you would like more information, talk with your healthcare provider. You may ask your
healthcare provider or pharmacist for information about
AVONEX that is written for healthcare professionals.
What are the ingredients in AVONEX?
• Vial with freeze-dried (lyophilized) powder:;albumin;(hu-man),;sodium;chloride,;dibasic;sodium;phosphate,;and
monobasic sodium phosphate.
•;Single-Use Prefilled Syringe: sodium acetate trihydrate,
glacial acetic acid, arginine hydrochloride, polysorbate
•;Single-Use Prefilled Autoinjector Pen: sodium acetate
trihydrate, glacial acetic acid, arginine hydrochloride,
and Drug Administration.