IS IT TIME TO RECONSIDER
YOUR TREATMENT?
TYSABRI® has been proven to reduce relapses.
You know how debilitating relapses can be in your life. So if
you’ve had any relapses recently, it may be time to talk with
your doctor about a different therapy for your relapsing multiple
sclerosis (MS). At the end of a 2-year study, TYSABRI reduced
how often flare-ups occurred by 67% compared with placebo.
The average number of flare-ups a person had each year was
0.22 for TYSABRI and 0.67 for placebo.
Please see below for Important Safety Information
about TYSABRI.
Indication
TYSABRI is a prescription medicine
approved for adult patients with
relapsing forms of MS to slow the
worsening of physical disability that is
common in patients with MS and
decrease the number of flare-ups
(relapses). Because TYSABRI
increases the risk of progressive
multifocal leukoencephalopathy
(PML), a rare brain infection that
usually causes death or severe
disability, TYSABRI is generally
recommended for patients that
have not been helped enough by,
or cannot tolerate, another treatment
for MS. TYSABRI does not cure MS
and has not been studied for longer
than 2 years or in patients with
chronic progressive MS.
Important Safety Information about TYSABRI
• TYSABRI increases your chance of getting a rare brain infection that usually
causes death or severe disability. This infection is called progressive multifocal
leukoencephalopathy (PML). PML usually happens in people with weakened
immune systems. No one can predict who will get PML. Your chances may be
higher if you are also being treated with medicines that weaken your immune
system, including other MS treatments. If you use TYSABRI alone to treat your
MS, you can still get PML. Your chance of getting PML increases with a longer
period of treatment or if you have received medicines that can weaken your
immune system prior to starting TYSABRI. However, PML is a rare event. There
is no known treatment, prevention, or cure for PML.
• If you take TYSABRI, it is important to call your doctor right away if you have any
new or worsening medical problems (such as a new or sudden change in your
thinking, eyesight, balance, or strength or other problems) that have lasted over
several days. Tell all of your doctors that you are getting treatment with TYSABRI.
• If you get PML, your doctor will monitor you for certain new or worsening
symptoms that can happen suddenly after you get PML. Contact your doctor
right away if you think your general health status is getting worse.
• Because of the chance for PML, TYSABRI is generally recommended for
patients that have not been helped enough by, or cannot tolerate another
treatment for MS. TYSABRI is available only through the TOUCH® Prescribing
Program, which is a restricted distribution program. Only prescribers, patients
and infusion centers enrolled in the TOUCH Prescribing Program can prescribe,
receive, and infuse TYSABRI. Before you take TYSABRI, you and your doctor
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